Multiomic investigations of Body Mass Index reveal heterogeneous trajectories in response to a lifestyle intervention Your Body Mass Index (BMI) is used frequently as a proxy for your health—but depending on your body type it…
Heterogeneity in statin responses explained by variation in the human gut microbiome Statins are one of the most prescribed medications. Current estimates stand at over 200 million people across the world who take these medications…
Multiple early factors anticipate post-acute COVID-19 sequelae Over two years into the global pandemic, the scientific community has stepped up investigations into what is commonly referred to as “long COVID,” or health conditions resulting from…
Integrated analysis of plasma and single immune cells uncovers metabolic changes in individuals with COVID-19 Metabolite profiling in blood plasma and analyzing single-cell multi-omics can elucidate changes in the immune system in COVID-19 patients. In…
Untargeted longitudinal analysis of a wellness cohort identifies markers of metastatic cancer years prior to diagnosis It’s clear that catching cancer early improves survival. In this study we leverage our deep phenotyping analysis to see…
Longitudinal analysis reveals transition barriers between dominant ecological states in the gut microbiome An important part of the Pioneer 100 study was profiling the gut microbiome of study participants. We know the importance of gut…